Mesenchymal stem cells (MSC) are multipotent stem cells with a great capacity for self-renewal while maintaining their multi-potency. They can develop into specialized cells of the body such as chondrocytes, osteoblasts and adipocytes. MSCs can also differentiate into nerve cells, heart muscle cells, liver cells and endothelial cells. Their easy accessibility, exceptional genomic stability, and their capacity for tissue repair with few immunological and ethical issues make them the favorable cell type for experimental and clinical use. Many trials are underway using these cells to understand and treat osteoarthritis, sepsis, autoimmune diseases, graft versus host disease, Crohn’s disease, multiple sclerosis, systemic lupus erythematosus and systemic sclerosis.
rfBMSC-nm from JangoCell are mesenchymal stem cells isolated from a neonatal (day 18) male Fischer rat leg bone. rfBMSC-nm are cultured, passaged for purity, cryopreserved, and delivered frozen. Each vial contains >1 x 106 cells in 1 ml volume. rfBMSC-nm are characterized by flow cytometry with antibodies to CD90, CD105, CD45, and CD34. rfBMSC-nm are negative for mycoplasma, yeast, fungi, and bacteria. rfBMSC-nm are assured to further culture using the protocol provided by JangoCell.