Adipose-derived adult stem cells (ADSC) are multipotent cells with a great capacity for self-renewal while maintaining their multi-potency. They are ideal for application in regenerative therapies. ADSCS can differentiate into specialized cells of the body such as osteocytes, adipocytes, neural cells, vascular endothelial cells, cardiomyocytes, pancreatic β-cells, and hepatocytes. Their easy accessibility, low immunogenicity and their ability to secrete trophic factors, cytokines and chemokines make them the favorable cell type for experimental and clinical use. ADSCs are also demonstrated to have proangiogenic, immunomodulatory, anti-apoptotic, anti-inflammatory, and anti-scarring effects. Many trials are underway to understand the potential of these cells to use for a wide range of clinical conditions including skeletal tissue repair, ischemic injuries, myocardial infarction, soft tissue regeneration and immune disorders such as lupus, arthritis, Crohn’s disease, multiple sclerosis, diabetes mellitus, and graft-versus-host disease.
rADSC-ym from JangoCell are adipose-derived stem cells isolated from male adult Sprague Dawley rat adipose tissue. rADSC-ym are cultured, cryopreserved at passage two and delivered frozen. Each vial contains >1 x 106 cells in 1 ml volume. rADSC-ym are characterized by flow cytometry with antibodies to CD90 and CD45. rADSC-ym are negative for mycoplasma, yeast, fungi and bacteria. rADSC-ym are assured to further culture using the protocol provided by JangoCell.
Suggested Cell Culture Medium
JangoCell suggests a modified version of Minimum Essential Medium (MEM), Alpha 1X. Details of the media will be provided with shipment.