EZSphere™ cell culture dishes and plates are specifically designed with a proprietary micro-well surface within each well of the plate, which allows for many uniformly sized aggregates or organoids to grow per well. The surface is coated with a “very low binding” 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer, which allows cells to grow in suspension.
Three-dimensional (3D) cell culture systems have gained in popularity as invaluable tools in broad applications of cell biology. 3D spheroid or organoid models are a better representation of actual cell behavior and response than a typical two-dimensional monolayer of cells and have proven more physiologically relevant for modeling disease as well as testing treatments and for chemical/drug screening.
This plate is for you if you want to grow many uniformly sized and shaped aggregates for expansion or testing. This plate is a must-have for any laboratory interested in aggregate/spheroid/organoid formation and want to find out how their research could benefit from this next generation technology!
- Clear bottom in wells with proprietary (multiple) micro-well surface per well
- Very Low Binding surface in the micro-wells within each well to reduce cell adhesion to the well surface and allow cells to grow in suspension
- Multiple micro-wells within each well to increase the number of spheroids or aggregates that will form from your cell culture – this allows many more cell aggregates to form than in a standard ULA plate
- Uniformly sized micro-wells across the well surface, so that many uniformly sized and shaped aggregates will form in each well
- Easy visualization of spheroids or aggregates within each well, including automated visualization
- Easily culture your cells and treat in the same plate – perfect for treatment of test compounds or drug screening
- Embryoid Bodies (EBs) and induced pluripotent stem cells (iPSCs) proliferate while maintaining pluripotency (little differentiation using flow cytometry)
- Variety of plate and dish sizes for easy cell culture and subsequent assay
- Different sized plates and dishes for different cell types